2009”N�A‚UŒŽ

Pediatr Allergy Immunol. 2009 Jun 25.
Cow's milk allergy related pediatric constipation: Appropriate time of milk tolerance.
El-Hodhod MA, Younis NT, Zaitoun YA, Daoud SD.
Departments of Pediatrics, Ain Shams University and Ministry of Health and Population, Cairo, Egypt.
Cow's milk allergy (CMA) has different clinical presentations according to age. Based on this limited study, tolerance is better achieved after 12 months of strict cow's milk elimination.

J Child Health Care. 2009 Jun;13(2):116-27.
Dietary fibre, fluids and physical activity in relation to constipation symptoms in pre-adolescent children.
Jennings A, Davies GJ, Costarelli V, Dettmar PW.
Nutritional Epidemiology and Biostatistics, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK. amy.jennings@uea.ac.uk.
Children with constipation are advised frequently to increase their activity levels, fluids and fibre intake. Physical activity levels were found to be significantly higher in the children reporting constipation symptoms, with the most active children reporting low water intakes. This study has highlighted that constipation symptoms are a prevalent problem in children not seeking medical treatment.

Int J Food Sci Nutr. 2009 Jun 26:1-15.
Studies on effect of multiple heating/cooling cycles on the resistant starch formation in cereals, legumes and tubers.
Yadav BS, Sharma A, Yadav RB.
Department of Food Science & Technology, Ch. Devi Lal University, Sirsa, Haryana, India.

J Nutr. 2009 Jun;139(6):1257S-1262S.
Dietary fructose and glucose differentially affect lipid and glucose homeostasis.
Schaefer EJ, Gleason JA, Dansinger ML.
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Cardiovascular Research Laboratory, Friedman School of Nutrition Science and Policy, Tufts University School of Medicine, Boston, MA 02111, USA. ernst.schaefer@tufts.edu
Absorbed glucose and fructose differ in that glucose largely escapes first-pass removal by the liver, whereas fructose does not, resulting in different metabolic effects of these 2 monosaccharides. In short-term controlled feeding studies, dietary fructose significantly increases postprandial triglyceride (TG) levels and has little effect on serum glucose concentrations, whereas dietary glucose has the opposite effects. In our view, to decrease the current high prevalence of obesity, dyslipidemia, insulin resistance, and diabetes, the focus should be on restricting the intake of excess energy, sucrose, HFCS, and animal and trans fats and increasing exercise and the intake of vegetables, vegetable oils, fish, fruit, whole grains, and fiber.

PLoS One. 2009 Jun 24;4(6):e6026.
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.
Uronis JM, Muhlbauer M, Herfarth HH, Rubinas TC, Jones GS, Jobin C.
Department of Medicine and Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
We present the first direct demonstration that manipulation of the intestinal microbiota alters the development of CAC. The TLR/MyD88 pathway is essential for microbiota-induced development of CAC. Unlike findings obtained using the AOM/DSS model, we demonstrate that the severity of chronic colitis directly correlates to colorectal tumor development and that bacterial-induced inflammation drives progression from adenoma to invasive carcinoma.

J Agric Food Chem. 2009 Jun 18. [
Biotransformation of Sesaminol Triglucoside to Mammalian Lignans by Intestinal Microbiota.
Jan KC, Hwang LS, Ho CT.
Graduate Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan.

DNA Cell Biol. 2009 Jun 17.
A Mesocosm of Lactobacillus johnsonii, Bifidobacterium longum, and Escherichia coli in the Mouse Gut.
Denou E, Rezzonico E, Panoff JM, Arigoni F, Brussow H.
1 Nutrition and Health Department, Nestle Research Center , Lausanne, Switzerland .

World J Gastroenterol. 2009 Jun 21;15(23):2887-92.
Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients.
Kerckhoffs AP, Samsom M, van der Rest ME, de Vogel J, Knol J, Ben-Amor K, Akkermans LM.
Department of Gastroenterology, Heidelberglaan 100, Utrecht, The Netherlands. angelekerckhoffs@hotmail.com
Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology.

BMC Microbiol. 2009 Jun 9;9:123.
The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age.
Mariat D, Firmesse O, Levenez F, Guimar?es V, Sokol H, Dore J, Corthier G, Furet JP.
INRA, U910, Unite d'Ecologie et du Systeme Digestif, Domaine de Vilvert, 78350 Jouy-en-Josas, France. denis.mariat@jouy.inra.fr.
In this work we have confirmed that qPCR is a powerful technique in studying the diverse and complex fecal microbiota. Our work demonstrates that the fecal microbiota composition evolves throughout life, from early childhood to old age.

Obesity (Silver Spring). 2009 Jun 4.
Microbiota and SCFA in Lean and Overweight Healthy Subjects.
Schwiertz A, Taras D, Schafer K, Beijer S, Bos NA, Donus C, Hardt PD.
Institute of Microecology, Auf den Luppen 8, Herborn, Germany.
Obesity has recently been linked to the composition of human microbiota and the production of short chain fatty acids (SCFAs). Our results are in line with previous reports suggesting that SCFA metabolism might play a considerable role in obesity. However, our results contradict previous reports with regard to the contribution of various bacterial groups to the development of obesity and this issue remains controversial.Obesity (2009) doi:10.1038/oby.2009.167.

J Physiol. 2009 Jun 2.
The role of the intestinal microbiota in enteric infection.
Sekirov I, Finlay BB.
University of British Columbia.

Front Biosci. 2009 Jun 1;14:5107-17.
The gut microbiota ecology: a new opportunity for the treatment of metabolic diseases?
Burcelin R, Luche E, Serino M, Amar J.
Rangueil Institute of Molecular Medicine, I2MR, U858 Inserm, IFR31, Toulouse, France. remy.burcelin@inserm.fr
imbalance between the two dominant groups of beneficial bacteria, the Bacteroidetes and the Firmicutes, generates signals controlling the expression of genes by the epithelial intestinal cells. Genes involved in lipid metabolism such as the Fast Induced Adipocyte Factor have been considered as putative targets. In addition, bacterial extracts such as the lipopolysaccharides control the tone of the innate immune system thus regulating the general inflammatory status, insulin resistance, and adipose tissue plasticity. Therefore, strategies aimed at controlling the ecological mutualism between intestinal microflora and the host should lead to a new era of therapeutic and health benefits.

Appl Environ Microbiol. 2009 Jun;75(12):4175-84.
Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiota.
Martinez I, Wallace G, Zhang C, Legge R, Benson AK, Carr TP, Moriyama EN, Walter J.
Department of Food Science and Technology, University of Nebraska, Lincoln, 68583-0919, USA.

J Nutr. 2009 Jun;139(6):1095-102.
The bioavailability of apigenin-7-glucoside is influenced by human intestinal microbiota in rats.
Hanske L, Loh G, Sczesny S, Blaut M, Braune A.
German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Gastrointestinal Microbiology, 14558 Nuthetal, Germany.
We investigated the impact of human intestinal microbiota on bioavailability of the flavone apigenin-7-glucoside (A7G) by comparing germ-free and human microbiota-associated (HMA) rats. The ability of selected gut bacteria and the host intestinal mucosa to deglycosylate A7G was tested using cell extracts. Apigenin was formed by cytosolic extracts of Eubacterium ramulus and Bacteroides distasonis and by the microsomal fraction of the small intestinal mucosa of rats. Overall, human intestinal microbiota largely contributed to A7G metabolism, indicating its influence on the bioactivity of flavones.
FEMS Immunol Med Microbiol. 2009 Jun;56(1):80-7.
Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota.
Tanaka S, Kobayashi T, Songjinda P, Tateyama A, Tsubouchi M, Kiyohara C, Shirakawa T, Sonomoto K, Nakayama J.
Laboratory of Microbial Technology, Department of Bioscience and Biotechnology, Division of Microbial Science and Technology, Faculty of Agriculture, Graduate School, Kyushu University, Fukuoka, Japan.
The influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota was monitored in 26 infants including five antibiotic-treated (AT) subjects orally administered a broad-spectrum antibiotic for the first 4 days of life and three caesarean-delivered (CD) subjects whose mothers were intravenously injected by the similar type of antibiotics in the same period. These results indicate that antibiotic exposure at the beginning of life greatly influences the development of neonatal intestinal microbiota.

Exp Gerontol. 2009 Jun-Jul;44(6-7):440-6.
Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly.
Zwielehner J, Liszt K, Handschur M, Lassl C, Lapin A, Haslberger AG.
Department of Nutritional Sciences, University of Vienna, Austria.
This study aimed at determining ageing-related shifts in diversity and composition of key members of the fecal microbiota by comparing institutionalized elderly (n = 17, 78-94 years) and young volunteers (n = 17, 18-31 years). Despite high individual variations, our analyses indicate the composition of microbiota in the elderly comprises a less diverse subset of young healthy microbiota. SIGNIFICANCE AND IMPACT OF THE STUDY: A better understanding of the individual composition of the human microbiota and the effects of ageing might result in the development of specifically targeted supplementation for elderly citizens in order to support healthy ageing.

Appl Environ Microbiol. 2009 Jun;75(11):3572-9.
High-throughput quantitative analysis of the human intestinal microbiota with a phylogenetic microarray.
Paliy O, Kenche H, Abernathy F, Michail S.
Department of Biochemistry and Molecular Biology, Wright State University, Dayton, OH 45435, USA. oleg.paliy@wright.edu

Curr Opin Infect Dis. 2009 Jun;22(3):292-301.
Commensal bacteria, traditional and opportunistic pathogens, dysbiosis and bacterial killing in inflammatory bowel diseases.
Packey CD, Sartor RB.
Department of Medicine, Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

FEMS Microbiol Ecol. 2009 Jun;68(3):351-62.
Comparative assessment of human and farm animal faecal microbiota using real-time quantitative PCR.
Furet JP, Firmesse O, Gourmelon M, Bridonneau C, Tap J, Mondot S, Dore J, Corthier G.
INRA, U910, Unite d'Ecologie et de Physiologie du Systeme Digestif, Jouy-en-Josas, France. jean-pierre.furet@jouy.inra.fr

ISME J. 2009 Jun;3(6):745-51.
Microbiomic analysis of the bifidobacterial population in the human distal gut.
Turroni F, Marchesi JR, Foroni E, Gueimonde M, Shanahan F, Margolles A, van Sinderen D, Ventura M.
Department of Genetics, Biology of Microorganisms, Anthropology and Evolution, University of Parma, Parma, Italy.

Br J Cancer. 2009 Jun 16;16(6).
Urinary phytoestrogen excretion and prostate cancer risk: a nested case-control study in the Multiethnic Cohort.
Park SY, Wilkens LR, Franke AA, Le Marchand L, Kakazu KK, Goodman MT, Murphy SP, Henderson BE, Kolonel LN.
Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA.
Our findings suggest that high intake of isoflavones, as reflected by urinary excretion of daidzein and genistein, may be protective against prostate cancer.

Biosci Biotechnol Biochem. 2009 Jun;73(6):1456-9.
Effects of capsaicin and isoflavone on blood pressure and serum levels of insulin-like growth factor-I in normotensive and hypertensive volunteers with alopecia.
Harada N, Okajima K.
Department of Translational Medical Science Research, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Br J Cancer. 2009 Jun 2;100(11):1817-23.
Plasma phyto-oestrogens and prostate cancer in the European Prospective Investigation into Cancer and Nutrition.
Travis RC, Spencer EA, Allen NE, Appleby PN, Roddam AW, Overvad K, Johnsen NF, Olsen A, Kaaks R, Linseisen J, Boeing H, Nothlings U, Bueno-de-Mesquita HB, Ros MM, Sacerdote C, Palli D, Tumino R, Berrino F, Trichopoulou A, Dilis V, Trichopoulos D, Chirlaque MD, Ardanaz E, Larranaga N, Gonzalez C, Suarez LR, Sanchez MJ, Bingham S, Khaw KT, Hallmans G, Stattin P, Rinaldi S, Slimani N, Jenab M, Riboli E, Key TJ.
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7LF, UK. ruth.travis@ceu.ox.ac.uk
The results suggest that higher concentrations of circulating genistein may reduce the risk of
prostate cancer but do not support an association with plasma lignans.

Br J Cancer. 2009 Jun 2;100(11):1812-6.
Dietary isoflavone and the risk of colorectal adenoma: a case-control study in Japan.

Akhter M, Iwasaki M, Yamaji T, Sasazuki S, Tsugane S.
Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.
The observed ceiling effect associated with higher isoflavone intake suggests that a lower intake of dietary isoflavone might be associated with an increased risk of colorectal adenoma in Japanese populations.

Am J Clin Nutr. 2009 Jun;89(6):1920-6.
Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study.
Lee SA, Shu XO, Li H, Yang G, Cai H, Wen W, Ji BT, Gao J, Gao YT, Zheng W.
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203-1738, USA.
This large, population-based, prospective cohort study provides strong evidence of a protective effect of soy food intake against premenopausal breast cancer.

Nutrition. 2009 Jun;25(6):676-85.
Effect of genistein on insulin resistance, renal lipid metabolism, and antioxidative activities in ovariectomized rats.
Choi JS, Song J.
Division of Metabolic Disease, Center for Biomedical Sciences, National Institute of Health, Seoul, Korea.
Genistein may help to maintain normal kidney function through the alleviation of many ovariectomy-induced risk factors for renal damage, including an increased insulin resistance index, renal oxidative stress, lipid accumulation, and extracellular matrix protein expression.

J Pediatr Gastroenterol Nutr. 2009 Jun 23.
Prebiotics Improve Gastric Motility and Gastric Electrical Activity in Preterm Newborns.
Indrio F, Riezzo G, Raimondi F, Francavilla R, Montagna O, Valenzano ML, Cavallo L, Boehm G.
*Department of Pediatrics, University of Bari, Italy daggerLaboratory of Experimental Pathophysiology, National Institute for Digestive Diseases I.R.C.C.S., "Saverio de Bellis,", Italy double daggerDepartment of Pediatrics, University Federico II Policlinico, Naples, Italy paragraph signSophia's Children Hospital, Erasmus University, Rotterdam, The Netherlands.
Prebiotic oligosaccharides can modulate the electrical activity and the gastric emptying and may improve the intestinal tolerance of enteral feeding in preterm infants.

Acta Paediatr. 2009 Jun 23.
The effect of prebiotics in the management of neonatal hyperbilirubinaemia.
Bisceglia M, Indrio F, Riezzo G, Poerio V, Corapi U, Raimondi F.
Department of Pediatrics, Ospedale San Giovanni di Dio Via XXV Aprile, Crotone, Italy.
The addition of prebiotics to standard infant diet might represent a novel strategy to help control neonatal hyperbilirubinaemia.

J Agric Food Chem. 2009 Jun 24;57(12):5510-7.
Direct enzymatic production of oligosaccharide mixtures from sugar beet pulp: experimental evaluation and mathematical modeling.
Martinez M, Gullon B, Yanez R, Alonso JL, Parajo JC.
Department of Chemical Engineering, Faculty of Science, University of Vigo, As Lagoas, Ourense, Spain.

Clin Exp Allergy. 2009 Jun 8.
Clinical effects of kestose, a prebiotic oligosaccharide, on the treatment of atopic dermatitis in infants.
Shibata R, Kimura M, Takahashi H, Mikami K, Aiba Y, Takeda H, Koga Y.
Department of Pediatrics, Fukuoka National Hospital, Fukuoka, Japan.

Clin Nutr. 2009 Jun;28(3):237-42.
Prebiotic supplementation of formula in preterm neonates: a systematic review and meta-analysis of randomised controlled trials.
Srinivasjois R, Rao S, Patole S.
Department of Neonatology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia.

Exp Dermatol. 2009 Jun 23. [
Oral supplementation with Lactobacillus rhamnosus CGMCC 1.3724 prevents development of atopic dermatitis in NC/NgaTnd mice possibly by modulating local production of IFN-gamma.
Tanaka A, Jung K, Benyacoub J, Prioult G, Okamoto N, Ohmori K, Blum S, Mercenier A, Matsuda H.
Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Institute of Symbiotic Science and Technology, Graduate School, Tokyo University of Agriculture and Technology, Tokyo, Japan.

Appl Microbiol Biotechnol. 2009 Jun 16.
Quantification of live and dead probiotic bacteria in lyophilised product by real-time PCR and by flow cytometry.
Kramer M, Obermajer N, Bogovi? Matija?i? B, Rogelj I, Kmetec V.
Lek Pharmaceuticals d.d., Quality Control, Verovskova 57, 1526, Ljubljana, Slovenia, mateja.kramer@sandoz.com.

Arch Microbiol. 2009 Jun 13.
Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties.
Martins FS, Silva AA, Vieira AT, Barbosa FH, Arantes RM, Teixeira MM, Nicoli JR.
Departamento de Microbiologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, C.P. 486, Belo Horizonte, MG, 30161-970, Brazil.

J Pediatr Gastroenterol Nutr. 2009 Jun 9.
Probiotic Lactobacilli in Breast Milk and Infant Stool in Relation to Oral Intake During the First Year of Life.
Abrahamsson TR, Sinkiewicz G, Jakobsson T, Fredrikson M, Bjorksten B.
*Department of Clinical and Experimental Medicine, Division of Pediatrics, Linkoping University, Linkoping, Sweden daggerDepartment of Biomedical Lab Science, Malmo University, Malmo, Sweden double daggerDepartment of Clinical and Experimental Medicine, Division of Occupational and Environmental Medicine, Linkoping University, Linkoping, Sweden section signInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Stockholm, Sweden.
Lactobacillus reuteri may be detected in breast milk after oral supplementation to the mother and in almost all infants after oral supplementation during the first year of life, as well as occasionally in many untreated infants.

Br J Community Nurs. 2009 Jun;14(6):230-6.
Functional foods: what are the benefits?
Williamson C.
British Nutrition Foundation, London. c.williamson@nutrition.org.uk

Lipids Health Dis. 2009 Jun 11;8(1):21.
Lactic acid bacteria affect serum cholesterol levels, harmful fecal enzyme activity, and fecal water content.
Lee DK, Jang S, Baek EH, Kim MJ, Lee KS, Shin HS, Chung MJ, Kim JE, Lee KO, Ha NJ.
In vitro culture experiments were performed to evaluate the ability of Bifidobacterium spp. isolated from healthy Koreans (20~30 years old) to reduce cholesterol-levels in MRS broth containing polyoxyethanylcholesterol sebacate. Daily consumption of B. longum SPM1207 can help in managing mild to moderate hypercholesterolemia, with potential to improve human health by helping to prevent colon cancer and constipation.

Inflamm Bowel Dis. 2009 Jun 5.
Prevention of TNBS-induced colitis by different Lactobacillus and Bifidobacterium strains is associated with an expansion of gammadeltaT and regulatory T cells of intestinal intraepithelial lymphocytes.
Roselli M, Finamore A, Nuccitelli S, Carnevali P, Brigidi P, Vitali B, Nobili F, Rami R, Garaguso I, Mengheri E.
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Roma, Italy.
The 2 probiotic mixtures were able to prevent the TNBS-induced colitis; the L. acidophilus and B. longum mixture was the most effective. Other than an involvement of LPLs, our results report a novel importance of the IELs population in probiotic protection.

Appl Environ Microbiol. 2009 Jun 5.
Biochemical properties of two cinnamoyl esterases purified from a Lactobacillus johnsonii strain isolated from diabetic resistant rats' (BB-DR) stool samples.
Lai KK, Lorca GL, Gonzalez CF.
Genetics Institute, Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32610-3610 USA.

Am J Vet Res. 2009 Jun;70(6):735-40.
Evaluation of Lactobacillus rhamnosus strain GG for the prevention of atopic dermatitis in dogs.
Marsella R.
Blanche Saunders Dermatology Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610.

Curr Gastroenterol Rep. 2009 Jun;11(3):238-47.
Probiotics in pediatric inflammatory bowel diseases.
Gulati AS, Dubinsky MC.
Department of Pediatrics, Division of Pediatric Gastroenterology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. agulati@med.unc.edu

Antonie Van Leeuwenhoek. 2009 Jun;96(1):89-98.
Influence of Lactobacillus fermentum I5007 on the intestinal and systemic immune responses of healthy and E. coli challenged piglets.
Wang A, Yu H, Gao X, Li X, Qiao S.
State Key Laboratory of Animal Nutrition, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing, People's Republic of China.

Clin Nutr. 2009 Jun;28(3):318-24.
Effects of Lactobacillus acidophilus on gut microflora metabolic biomarkers in fed and fasted rats.
Mountzouris KC, Kotzampassi K, Tsirtsikos P, Kapoutzis K, Fegeros K.
Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, Agricultural University of Athens, Iera Odos 75, Athens, Greece. kmountzouris@aua.gr
The results indicate a health beneficial potential of L. acidophilus in fasted and re-fed nutritional states via reduction of harmful azoreductase and CGH activities and promotion of useful VFA components for colonic function and health.

J Basic Microbiol. 2009 Jun;49(3):318-26.
Isolation and preliminary probiotic selection of lactobacilli from koumiss in Inner Mongolia.
Wu R, Wang L, Wang J, Li H, Menghe B, Wu J, Guo M, Zhang H.
The Key Laboratory of Dairy Biotechnology and Bioengineering, Education Ministry of P.R. China, Department of Food Science and Engineering, Inner Mongolia Agricultural University, Huhhot, P.R. China.
The dominant lactobacilli species were identified as L. casei (17 strains), L. helveticus (10 strains) and L. plantarum (8 strains), with a lower frequency of isolation for L. coryniformis subsp. coryniformis (5 strains), L. paracasei (3 strains), L. kefiranofaciens (2 strains), L. curvatus (1 strain), L. fermentum (1 strain) and W. kandleri (1 strain). The pH values of all these samples were ranging from 3.37 to 3.94. In isolates, L. casei Zhang, L. helveticus ZL12-1, and L. plantarum BX6-6 were selected as potentially probiotic strains through the preliminary tests including resistance to low acid, abilities to grow in MRS with bile salts, antimicrobial activities and the viabilities during prolonged cold storage in fermented milk. Moreover 16S rDNA was conducted to confirm the identification.

Dig Dis Sci. 2009 Jun;54(6):1222-8.
Small-intestinal manifestations of dextran sulfate sodium consumption in rats and assessment of the effects of Lactobacillus fermentum BR11.
Geier MS, Smith CL, Butler RN, Howarth GS.
Centre for Paediatric and Adolescent Gastroenterology, Children, Youth and Women's Health Service, North Adelaide, Adelaide, SA, Australia.
While DSS predominantly induces colonic damage, minor morphological alterations were also detected in the distal small intestine. L. fermentum BR11 normalized these features.

Biosci Biotechnol Biochem. 2009 Jun;73(6):1280-5.
Effect of white wheat bread containing sugar beet fiber on serum lipids and hepatic mRNA in rats fed on a cholesterol-free diet.
Nakamura Y, Kanazawa M, Liyanage R, Iijima S, Han KH, Shimada K, Sekikawa M, Yamauchi A, Hashimoto N, Ohba K, Fukushima M.
Department of Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.

Blood. 2009 Jun 18;113(25):6440-8.
Short-chain fatty acid-mediated effects on erythropoiesis in primary definitive erythroid cells.
Bhatia H, Hallock JL, Dutta A, Karkashon S, Sterner LS, Miyazaki T, Dean A, Little JA.
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Behav Brain Res. 2009 Jun 8;200(1):33-41.
Intracerebroventricular injections of the enteric bacterial metabolic product propionic acid impair cognition and sensorimotor ability in the Long-Evans rat: further development of a rodent model of autism.
Shultz SR, Macfabe DF, Martin S, Jackson J, Taylor R, Boon F, Ossenkopp KP, Cain DP.
The Kilee Patchell-Evans Autism Research Group, Department of Psychology and Graduate Program in Neuroscience, University of Western Ontario, London, Canada. sshultz@uwo.ca
Propionic acid (PPA) is a dietary short chain fatty acid and a metabolic end-product of enteric bacteria. Intracerebroventricular (ICV) injections of PPA can result in brain and behavioral abnormalities in rats similar to those seen in humans suffering from autism. Compared to controls, PPA-treated rats were impaired in the water maze task as indicated by an unusual pattern of mild or no impairment during spatial acquisition training, but marked impairment during spatial reversal training. PPA-treated rats were also impaired on the beam task. Neuropathological analysis from PPA-treated rats revealed an innate neuroinflammatory response. These findings add to evidence that PPA can change the brain and behavior in the laboratory rat consistent with symptoms of human autism.